Essay about American Capitalism - 3831 Words

American Capitalism Capitalism - An economic and political system in which a countrys trade and industry are controlled by private owners for profit, rather than by the state. America was an ideal breeding ground for capitalism, a relatively new country, in need of young entrepreneurs to kick start its already buoyant economy. The country was an ideal place to get rich quick, an idea that inspired the immigrants that poured into it each year. In America it seemed you could turn your rags to riches in no time at all. Its this idea that fueled the American Dream Capitalism was motivated in the 20s by the Republican government. They believed in non-interference or laissez faire, the†¦show more content†¦People facing religious or political persecution, or just plain poverty came to America to alleviate themselves from negative aspects of life. This was an important part of the American dream as it made many immigrants cross the seas to seek this liberty. On the surface American capitalism seemed to be helping the country no-end. There were several visible indications of the prosperity. Mass production meant that technological advances such as washing machines and hovers became available to many families. The inflating wages helped to fund the new streak of consumerism that swept the country, Americas wages were far higher than any comparitable jobs over the world. New motor cars were popping up all over the place, thanks to Henry Ford, a figure often used to symbolise the American dream as he was so successful, and even today is a household name. A newly founded advertising industry worked its tricky magic amongst the susceptible citizens, making goods seem all the more glamorous. Easy credit helped in the purchase of the goods once a person was dedicated to enriching their life with it. For those who lived far from shops and arcades came mail order catalogues and travelling salesmen, meaning people all over America could enjoy th e wonders of consumerism. Prosperity could also been seen in the low unemployment rates, helped considerably by the roaring construction industry,Show MoreRelatedCritique Of American Capitalism And Capitalism2411 Words   |  10 PagesCapitalism is not a rigid, inflexible economic and political system—there are many forms of capitalism around the world. It is illustrated as being different variations of capitalism outside the United States; there is the Dutch version, the French version, the British version, as well as the American version. American capitalism implements free-market ideology and that makes the U.S. stand out among other nations. Other nations do not dwell on privatization and deregulation nearly as much as theRead MoreEssay on American Capitalism 2283 Words   |  10 PagesAlthough it holds true that the United States is a global power, the current economic system, capitalism, threatens the states domestic and global stability; the concept of materialistic success creates inequalities between citizens, which, in turn, leads to deviance and rebellion, and the possibility of a fallen capitalistic society. If the United States were to struggle internally, one of two things would happen: all industrialized external forces would exploit on Americas lack of equanimityRead MoreThe Corporate American Model Of Capitalism1316 Words   |  6 PagesCapitalism is good. In reading the articles, it seems scholars are either pro or anti-capitalism. The corporate American model of capitalism is built upon free enterprise and encourages competition. It’s also called the Liberal/Social Democratic model. Our economy, supposedly, encourages and rewards competition and equality. Yet the lack of competition and equality in our economy are issues scholars take aim at the most. George (2013) wrote in his editorial, â€Å"In the United States, income inequalityRead MoreBenefits And Drawbacks Of American Capitalism996 Words   |  4 Pagesand drawback s to American Capitalism. Capitalism is the idea of a free market based economy wherein that economy is organized by individual people and companies rather than the government. This type of economy, in essence, promotes cheaper goods bought and sold, less waste, economic growth, innovation, and overall fairness. However, the American dream is not all it takes in order to pave a path to economic success in our society. In fact, some would argue that American capitalism is the very foundationRead MoreAmerican Capitalism And The Economic System1324 Words   |  6 Pages Wealthy disparity in America is greater than it has ever been, yet nothing seems to be done by the government to fix it. Bridging the wealth gap in America would require government regulation from government, but the American government is controlled by the wealthy. Rich business owners give large sums of money towards political campaigns, thus gaining them political favor. Along with a corrupted government, large corporations have taken up almost all market share in their respective industriesRead MoreAmericans love freedom we love money we love capitalism. Capitalism is most definitely an1200 Words   |  5 PagesAmericans love freedom; we love money; we love capitalism. Capitalism is most definitely an element of dominant culture amongst the citizens of the United States. In American culture it is easy to see that many of our institutions, including public schools, indoctrinate the children whom they serve with a common American idealism: capitalism is good, communism is bad. Being a citizen of the United States and not being a capitalist is verging upon the fringe of an unwritten taboo. If there isRead MoreCapitalism And The American Worker1331 Words   |  6 PagesThroughout the 19th and 20th century capitalism was on a rise and many writers had different perspectives on the positives and negatives of capitalism and how it shaped America. Thomas DiLorenzo who wrote How Capitalism Enriched the Working Class, focused on how the world became better because of capitalism. Melvyn Dubofsky’s Industrialism and the American Worker, focused on how the lives of working people were deteriorated because of the development of labor and what conditions these people facedRead MoreSlavery And The Making Of American Capitalism1153 Words   |  5 PagesJose Arciga Robert Dean History 110 11.10.15 Essay Prompt The Half Has Never Been Told :Slavery and the making of American Capitalism Back when America was being shaped, tobacco was the main slave produced trade in the colonies. Plantations all across the south had a majority of the slaves from Africa brought here on ships. Forced to work for their slave owners. Tobacco wasn t the only booming business. Cotton soon came into the picture, the north was a more industrial economy, while the southRead MoreAmerican Capitalism And Soviet Communism1344 Words   |  6 Pages American capitalism and Soviet Communism were incompatible systems; Washington shouldn’t have been surprised to hear this in George Kennan’s long telegram. But the tensions were not always this high between the two word powers. In the end of world war two, â€Å"Stalin s empire was won with reservoirs of soviet blood†(cite 1). The thought to be never ending Soviet army was not limitless anymore. The estimated cost of the war was at 2.6 trillion(cite 4), with most of the population wanting to focusRead MoreThe Battle of European Socialism vs. American Capitalism2286 Words   |  10 PagesBattle of European Socialism vs. American Capitalism† Let the battle begin, on the left we have European Socialism and on the right we have American Capitalism! Round One: What is Capitalism? Capitalism is regarded as an economic system and a political strategy distinguished by certain characteristics whose development is conditioned by numerous variables. So how is Capitalism viewed in the United States of America? American Capitalism can be viewed in multiple fashions:

Revised GRE Free Essays

[pic] GRADUATE RECORD EXAMINATIONS ® Practice General Test #1 Answer Key for Sections 1-4 Copyright  © 2010 by Educational Testing Service. All rights reserved. ETS, the ETS logo, GRADUATE RECORD EXAMINATIONS, and GRE are registered trademarks of Educational Testing Service (ETS) in the United States and other countries. We will write a custom essay sample on Revised GRE or any similar topic only for you Order Now Revised GRE ® Practice Test Number 1 Answer Key for Section 1. Verbal Reasoning. 25 Questions. Question 1 Answer: A. In various parts of the world, civilizations that could not make iron from ore fashioned tools out of fragments of iron from meteorites. Question 2 Answer: A. An increased focus on the importance of engaging the audience in a narrative Question 3 Answer: C. speak to Question 4 Answer: A. People with access to an electric washing machine typically wore their clothes many fewer times before washing them than did people without access to electric washing machines. Question 5 Answer: C. insular Answer in context: In the 1950’s, the country’s inhabitants were insular: most of them knew very little about foreign countries. Question 6 Answer: E. insincere Answer in context: Since she believed him to be both candid and trustworthy, she refused to consider the possibility that his statement had been insincere. Question 7 Answer: A. maturity Answer in context: It is his dubious distinction to have proved what nobody would think of denying, that Romero at the age of sixty-four writes with all the characteristics of maturity. Question 8 Answer: C. comparing two scholarly debates and discussing their histories Question 9 Answer: D. identify a reason for a certain difference in the late 1970’s between the origins debate and the debate over American women’s status Question 10 Answer: D. Their approach resembled the approach taken in studies by Wood and by Mullin in that they were interested in the experiences of people subjected to a system of subordination. Question 11 Answer: A. gave more attention to the experiences of enslaved women Question 12 Answer: A. construe F. collude in Answer in context: The narratives that vanquished peoples have created of their defeat have, according to Schivelbusch, fallen into several identifiable types. In one of these, the vanquished manage to construe the victor’s triumph as the result of some spurious advantage, the victors being truly inferior where it counts. Often the winners collude in this interpretation, worrying about the cultural or moral costs of their triumph and so giving some credence to the losers’ story. Question 13 Answer: B. settled E. ambiguity G. similarly equivocal Answer in context: I’ve long anticipated this retrospective of the artist’s work, hoping that it would make settled judgments about him possible, but greater familiarity with his paintings highlights their inherent ambiguity and actually makes one’s assessment similarly equivocal. Question 14 Answer: A. a debased E. goose bumps Answer in context: Stories are a haunted genre; hardly a debased kind of story, the ghost story is almost the paradigm of the form, and goose bumps was undoubtedly one effect that Poe had in mind when he wrote about how stories work. Question 15 Answer: C. patent E. improbable Answer in context: Given how patent the shortcomings of the standard economic model are in its portrayal of human behavior, the failure of many economists to respond to them is astonishing. They continue to fill the journals with yet more proofs of yet more improbable theorems. Others, by contrast, accept the criticisms as a challenge, seeking to expand the basic model to embrace a wider range of things people do. Question 16 Answer: B. startling D. jettison Answer in context: The playwright’s approach is startling in that her works jettison the theatrical devices normally used to create drama on the stage. Question 17 Answer: B. create F. logical Answer in context: Scientists are not the only persons who examine the world bout them by the use of rational processes, although they sometimes create this impression by extending the definition of â€Å"scientist† to include anyone who is logical in his or her investigational practices. Question 18 Answer: C. It presents a specific application of a general principle. Question 19 Answer: A. outstrip Question 20 Answer: B. It is a mistake to think that the natural world contains many areas of pristine wilderness. Question 21 Answer: C. coincident with Question 22 Sentence to be Completed: Dreams are BLANK in and of themselves, but, when combined with other data, they can tell us much about the dreamer. Answer: D. inscrutable, F. uninformative Question 23 Sentence to be Completed: Linguistic science confirms what experienced users of ASL—American Sign Language—have always implicitly known:   ASL is a grammatically BLANK language, as capable of expressing a full range of syntactic relations as any natural spoken language. Answer: A. complete, F. unlimited Question 24 Sentence to be Completed: The macromolecule RNA is common to all living beings, and DNA, which is found in all organisms except some bacteria, is almost as BLANK. Answer: D. universal, F. ubiquitous Question 25 Sentence to be Completed: Early critics of Emily Dickinson’s poetry mistook for simple-mindedness the surface of artlessness that in fact she constructed with such BLANK. Answer: B. craft, C. cunning This is the end of the answer key for Revised GRE Practice Test 1, Section 1. Revised GRE Practice Test Number 1 Answer Key for Section 2. Verbal Reasoning. 25 Questions. Question 1 Sentence to be Completed: In the long run, high-technology communications cannot BLANK more traditional face-to-face family togetherness, in Aspinall’s view. Answer: C. supercede, F. supplant Question 2 Sentence to be Completed: Even in this business, where BLANK is part of everyday life, a talent for lying is not something usually found on one’s resume. Answer: B. mendacity, C. prevarication Question 3 Sentence to be Completed: A restaurant’s menu is generally reflected in its decor; however despite this restaurant’s BLANK appearance it is pedestrian in the menu it offers. Answer: A. elegant, F. chic (spelled C H I C) Question 4 Sentence to be Completed: International financial issues are typically BLANK by the United States media because they are too technical to make snappy headlines and too inaccessible to people who lack a background in economics. Answer: A. neglected, B. slighted Question 5 Sentence to be Completed: While in many ways their personalities could not have been more different—she was ebullient where he was glum, relaxed where he was awkward, garrulous where he was BLANK—they were surprisingly well suited. Answer: D. laconic, F. taciturn Question 6 Answer: D. spirituals Question 7 Answer: B. They had little working familiarity with such forms of American music as jazz, blues, and popular songs. Question 8 Answer: E. neglected Johnson’s contribution to classical symphonic music Question 9 Answer: C. The editorial policies of some early United States newspapers became a counterweight to proponents of traditional values. Question 10 Answer: A. insincerely Question 11 Answer: Blank 1 C. multifaceted Blank 2 F. extraneous Answer in context: The multifaceted nature of classical tragedy in Athens belies the modern image of tragedy:   in the modern view tragedy is austere and stripped down, its representations of ideological and emotional conflicts so superbly compressed that there’s nothing extraneous for time to erode. Question 12 Answer: Blank 1 C. ambivalence Blank 2 E. successful Blank 3 H. assuage Answer in context: Murray, whose show of recent paintings and drawings is her best in many years, has been eminent hereabouts for a quarter century, although often regarded with ambivalence, but the most successful of these aintings assuage all doubts. Question 13 Answer: B. a doctrinaire Answer in context: Far from viewing Jefferson as a skeptical but enlightened intellectual, historians of the 1960’s portrayed him as a doctrinaire thinker, eager to fill the young with his political orthodoxy while censoring ideas he did not like. Question 14 Answer: C. recapitulates Answer in context: Dr amatic literature often recapitulates the history of a culture in that it takes as its subject matter the important events that have shaped and guided the culture. Question 15 Answer: E. ffirm the thematic coherence underlying Raisin in the Sun Question 16 Answer: C. The painter of this picture could not intend it to be funny; therefore, its humor must result from a lack of skill. Question 17 Answer: E. (Sentence 5) But the play’s complex view of Black self-esteem and human solidarity as compatible is no more â€Å"contradictory† than DuBois’s famous, well-considered ideal of ethnic self-awareness coexisting with human unity, or Fanon’s emphasis on an ideal internationalism that also accommodates national identities and roles. Question 18 Answer: C. Because of shortages in funding, the organizing committee of the choral festival required singers to purchase their own copies of the music performed at the festival. Question 19 Answer: Blank 1 C. mimicking Blank 2 D. transmitted to Answer in context: New technologies often begin by mimicking what has gone before, and they change the world later. Think how long it took power-using companies to recognize that with electricity they did not need to cluster their machinery around the power source, as in the days of steam. Instead, power could be transmitted to their processes. In that sense, many of today’s computer networks are still in the steam age. Their full potential remains unrealized. Question 20 Answer: Blank 1 B. opaque to Blank 2 D. an arcane Answer in context: There has been much hand-wringing about how unprepared American students are for college. Graff reverses this perspective, suggesting that colleges are unprepared for students. In his analysis, the university culture is largely opaque to entering students because academic culture fails to make connections to the kinds of arguments and cultural references that students grasp. Understandably, many students view academic life as an arcane ritual. Question 21 Answer: Blank 1 C. defiant Blank 2 D. disregard for Answer in context: Of course anyone who has ever perused an unmodernized text of Captain Clark’s journals knows that the Captain was one of the most defiant spellers ever to write in English, but despite this disregard for orthographical rules, Clark is never unclear. Question 22 Answer: A. There have been some open jobs for which no qualified FasCorp employee applied. Question 23 Answer: C. presenting a possible explanation of a phenomenon Question 24 Two of the answer choices are correct: A. The pull theory is not universally accepted by scientists. B. The pull theory depends on one of water’s physical properties. Question 25 Answer: E. the mechanism underlying water’s tensile strength This is the end of the answer key for Revised GRE Practice Test 1, Section 2. Revised GRE Practice Test Number 1 Answer Key for Section 3. Quantitative Reasoning. 25  Questions. Question 1 Answer: A. Quantity A is greater. Question 2 Answer: BQuantity B is greater. Question 3 Answer: BQuantity B is greater. Question 4 Answer: D. The relationship cannot be determined from the information given. Question 5 Answer: D. The relationship cannot be determined from the information given. Question 6 Answer: A. Quantity A is greater. Question 7 Answer: D. The relationship cannot be determined from the information given. Question 8 Answer: C. The two quantities are equal. Question 9 Answer: D. The relationship cannot be determined from the information given. Question 10 Answer: B. [pic] three halves Question 11 Answer: The answer to question 11 consists of four of the answer choices. A. 12 ° B. 15 ° C. 5 ° D. 50 ° Question 12 Answer: A. 10 Question 13 Answer: D. 15 Question 14 Answer: A. 299 Question 15 Answer: In question 15 you were asked to enter either an integer or a decimal number. The answer to question 15 is 3,600. Question 16 Answer: A. 8 Question 17 Answer: In question 17 you were asked to enter either an integer or a decimal number. The answer to question 17 is 250. Question 18 Answer: C. Three Quest ion 19 Answer: B. Manufacturing. Question 20 Answer: A:5. 2 Question 21 Answer: B. More than half of the titles distributed by M are also distributed by L. Question 22 Answer: A. c  +  d Question 23 Answer: In question 23 you were asked to enter either an integer or a decimal. The answer to question 23 is 36. 5. Question 24 Answer: D. [pic] two fifths Question 25 Answer: D. [pic] three halves This is the end of the answer key for Revised GRE Practice Test 1, Section 3. Revised GRE Practice Test Number 1 Answer Key for Section 4. Quantitative Reasoning. 25   Questions. Question 1 Answer: A. Quantity A is greater. Question 2 Answer: D. The relationship cannot be determined from the information given. Question 3 Answer: D. The relationship cannot be determined from the information given. Question 4 Answer: D. The relationship cannot be determined from the information given. Question 5 Answer: B. Quantity B is greater. Question 6 Answer: A. Quantity A is greater. Question 7 Answer: C. The two quantities are equal. Question 8 Answer: A. Quantity A is greater. Question 9 Answer: C. The two quantities are equal. Question 10 Answer: D:j  k  +  j Question 11 Answer: In question 11 you were asked to enter a fraction. The answer to question 11 is the fraction [pic] one over four. Question 12 Answer: The answer to question 12 consists of four of the answer choices. B. $43,350 C. $47,256 D. $51,996 E. $53,808 Question 13 Answer: E. 676,000 Question 14 Answer: E. [pic] s squared minus p squared Question 15 Answer: B. [pic] k minus 1 Question 16 Answer: B. 110,000 Question 17 Answer: B:3 to 1 Question 18 Answer: E. 1,250 Question 19 Answer: C:948 Question 20 Answer: The answer to question 20 consists of two answer choices. B. Students majoring in either social sciences or physical sciences constitute more than 50 percent of the total enrollment. C. The ratio of the number of males to the number of females in the senior class is less than 2 to 1. Question 21 Answer: B. [pic] 33 and 1 third percent Question 22 Answer: A. 12 Question 23 Answer: D. 4,400 Question 24 Answer: In question 24 you were asked to enter either an integer or a decimal number. The answer to question 24 is 10. Question 25 Answer: The answer to question 25 consists of 5 answer choices. B. 3. 0 C. 3. 5 D. 4. 0 E. 4. 5 F. 5. 0 This is the end of the answer key for Revised GRE Practice Test 1, Section 4. How to cite Revised GRE, Essay examples

Case Study Report Co-Morbidities

Question: Discuss about theCase Study Report for Co-Morbidities. Answer: Introduction: There is ample evidence available for the link between type 2 diabetes, obesity, hypertension, renal disease and comorbid conditions of these disease conditions are well researched. People with obesity are 2.3 billion and type 2 diabetes are 365 million (Kawano and Arora, 2009). Particularly, in the older age people, there is the occurrence of chronic comorbid conditions of the above mentioned disease conditions rather than the occurrence of the individual disease. These comorbid diseases are more serious health issues and it is difficult to control these conditions. In this report, a patient with the occurrence of comorbid conditions of type 2 diabetes, overweight, hypertension, renal dysfunction, retinopathy and oedema is presented. The question here is how would a person develops different disease conditions? Is there any connecting link among these comorbid disease conditions? Pathophysiology of each of these conditions is being described and different pathways and biomarkers con necting these disease conditions are being mentioned. Also evidence for the occurrence of these comorbid conditions is described. Discussion: Type 2 Diabetes: This patient is diagnosed with type 2 diabetes. Type 2 diabetes mellitus is the most common form of diabetes i.e. increases in sugar level in the body. Fasting glucose level should be below 140 mg/dl and random blood glucose level should be below 180 mg/dl. Type 2 diabetes occurs either due to the resistance to the action of insulin or insufficient secretion of insulin from the beta cells of the islets of Langerhans. This insulin resistance, mainly occurs in the liver, skeletal muscle and adipose tissue. Binding of insulin to its receptor results in the tissue specific actions such as inhibition of glucose production by liver, promotion of glucose uptake by skeletal muscle and inhibition of lipolysis in adipose tissue. In case of insulin resistance, there is the disturbance in the suppression of glucose production by liver, clearance of glucose by the liver and promotion of lipolysis by adipose tissue (Olefsky and Glass, 2010). In type 2 diabetes, beta cells become dysfunctional and there is no control of hyperglycaemia. Free fatty acids also induces, insulin resistance specifically in muscle by disturbing insulin signalling pathway. One of the intermediate products of triglyceride metabolism, diacylglycerol activates protein kinase C, which phosphorylate serine and threonine residues located at the insulin receptor and insulin receptor substrate, which results in the insulin resistance. Incretins are metabolic hormones, which stimulate insulin release and inhibit glucagon release. Hence, deficiency of incretins leads to the type 2 diabetes. Glucagon is a peptide hormone secreted by the alpha cells of the pancreas and it increases the glucose level by gluconeogenesis (glucose synthesis by liver and kidney) and glycogenolysis (breakdown of glycogen in glucose). Type 2 diabetes mellitus affects different body organs and their respective systems. It procures dyslipidaemia and hypertension. In case of dyslipidaemia, there is the increase in cholesterol (~60 %), low density lipoprotein (LDL)-cholesterol (~41 %) and triglycerides (~51%) of the total cases. In another study, it has been quoted that about 65 % people have increased triglyceride and decreased high density lipoprotein (HDL) (Mayer-Davis et al., 2009; Tryggestad and Willi, 2015). Type 2 Diabetes and Renal Complication Comorbidity: With this mentioned patient, there is the renal complication due to the type 2 diabetes. In the previous studies, it is evident that around 18-72 % type 2 diabetes patients developed nephropathy in the form of microalbuminuria and abnormal albumin to creatinine ratio (Tryggestad and Willi, 2015). Elevated levels of protein and glucose in the urine reflect proteinuria and diabetes, respectively and both these conditions leads to the renal failure. This proteinuria is associated with obesity and diabetes. In these type 2 diabetes patients there is the increase in the renal plasma flow and 25-50 % increase in the glomerular filtration rate. Increased reabsorption of the glucose and sodium in the proximal tubule is responsible for the increased glomerular filtration rate (Helal et al., 2012; Vallon, and Thomson, 2012). Hyperglycaemia also begins formation of advanced glycation end products (AGEs), increased expression of AGE receptor (RAGE), activation of polyol, hexosamine pathways and activation of protein kinase C (pkc) pathway. Oxidative stress in the mitochondria leads to the production of inflammatory cytokines like Interleukin-1 (IL-1), IL-6 and Tumor necrosis factor alpha (TNF-) and profibrotic growth factors like Transforming growth factor (TGF) and Vascular endothelial growth factor (VEGF). All these factors lead to the renal injury (Navarro-Gonzlez et al., 2011; Muskiet et al., 2014). This complex health condition affects patient and his family very seriously. Three can be possibility that patient can feel social withdrawal. That can be due to the frequent urination due to the renal complication in the patient. Also, patient loses his freedom on the food to be consumed due to diabetes. This also makes patient family low, however patient family should try to uplift patient moral. Overweight Condition: It is observed that mentioned patient is overweight. In overweight patient body mass index (BMI) should be between 25-30. Overweight condition results due to the imbalance in the energy intake and expenditure. There is the increase in the adipose tissue in the overweight people. There is the increase in the level of leptin, TNF-alpha, IL-6, angiotensin, plasminogen activator inhibitor and resistin in the overweight people. On the other hand, there is a decrease level of adiponectin in overweight people. Leptin is produced by the adipose tissue and considered as the satiety factor which gives signals of excess fat reserve in the body and bring about appetite control. However, most of the overweight people are leptin resistant. Along with the function as energy reservoir, adipose tissue also secrets adipokines like cytokines, hormones, growth factors, acute phase proteins, prostaglandins, glucocorticoids and sex steroids. In overweight people macrophages are permeated into the adipose tissue and consequently shift from macrophage M2 to macrophage M1 occurs. These hypertrophied adipose tissue along with M1 secrets proinflammatory cytokines like TNF-alpha and IL-6 (Maury and Brichard , 2010 ; Schmidt et al., 2015). Renin-angiotensin system in adipose tissue is an important connects for the association of obesity and hypertension. Angiotensin II plays a role in adipose tissue growth and differentiation (Mehri et al., 2010; Kalupahana and Moustaid-Moussa, 2012). Adiponectin is a collagen-like protein secreted by adipose tissues. Adiponectin induces energy expenditure. As there is less secretion of adiponectin in overweight people, energy expenditure is less. In mentioned patient there is the comorbid condition of overweight and type 2 diabetes. Occurrence of type 2 diabetes is more in the overweight people as compared to the type 1 diabetes. It is found that around 30 % overweight people are susceptible to the development of type 2 diabetes (Wang et al., 2015). Due to increase in the free fatty acids in the overweight patients, there is the decompensation of insulin producing beta cells and insulin resistance. These fatty acids get oxidised and produces reactive oxygen species, which activates IKK, NFk, TNF and JNK pathway. This JNK phosphorylate insulin receptor and produces decreased insulin signalling and insulin resistance. Overweight and Hypertension Comorbid Condition: Along with the overweight condition and type 2 diabetes, there is the elevated blood pressure in the mentioned patient. Around 25 % overweight people developed hypertension as compared to the normal people (Luo et al., 2013). Overweight people are associated with increased blood flow and hypertension. Increased leptin in the overweight people also produces hypertension through sympathetic activation. There is the increased renin activity in the overweight people, which activates renin-angiotensin system and results in the hypertension through sympathetic activation. Also there is the increased secretion of insulin in the overweight people, this insulin also stimulate renal reabsorption of sodium and leads to the hypertension (Richard., 2009). In overweight people renal dysfunction is more as compared to the normal people (Franchini et al., 2015). Increased level of the leptin in the obesity is responsible for the proteinuria. In overweight people, adipocytes exert inflammatory and en docrine function and produces vascular damage in the kidneys. Hence, there is the increased hyperfiltration and glomerular filtration rate (GFR), albumin excretion rate (AER) and microalbuminuria (Sanad and Gharib, 2011). In overweight people adipose tissue releases leptin, this stimulates aldosterone release from adrenal gland which is responsible for sodium retention and hypertension. Due to overweight and hypertension comorbid condition, patient cannot do more physical activity and cannot tolerate more stress. Patient may feel isolated in the social life. Due to this inactive state of patient, one of the family members should always be with the patient to take care of him. In this case family members cannot concentrate on their personal and professional work. This affects social and financial status of the family. Diabetic Retinopathy: Diabetic retinopathy, which is caused due to the increased retinal vascular permeability resulted in the vascular proliferation and vision loss. Diabetic retinopathy occurs in around 40-60 % patients with non-existing retinopathy and progression of retinopathy in around 30 % patients with existing retinopathy (Mayer-Davis et al., 2012). Hypertension: Normal blood pressure range is 100-140 mmHg systolic and 60-90 mmHg diastolic. Hypertension is considered if blood pressure is consistently above 140 mmHg systolic and 90 mmHg diastolic (Mancia et al., 2013). In hypertension, there is the increased resistance to blood flow i.e. increased peripheral resistance due to the narrowing of the small arteries and arterioles and also due to the less number of capillaries. Reduced peripheral venous compliance also plays role in hypertension, which causes venous return, elevate cardiac preload and finally results in the diastolic dysfunction. Main mechanisms involved in the hypertension are dysfunctional renin-angiotensin system, atypical sympathetic nervous system, insulin resistance, endothelial dysfunction and vascular inflammation. Renin stimulates adrenal gland to secret more aldosterone through reninangiotensinaldosterone system (RAAS), which induces sodium retention, which is responsible for hypertension. The sympathetic nervous system a lso acts through the same pathway by activating the RAAS system in the kidney. Excessive oxidative stress and vascular inflammation are responsible for the hypertension in the endothelial dysfunction. There is the increased activity of oxidative stress marker i.e. nicotinamide adenine dinucleotide phosphate (NADPH) oxidase in the hypertension (Dharmashankar and Widlansky, 2013). There is the increased production of inflammatory cytokines like Interleukin-17 (IL-17), IL-1, IL-6, IL-8 and TNF in the hypertensive patients. (Gooch and Sharma, 2013). Hypertension has been reported to be in the range of 30-65 % patients with type 2 diabetes (Mayer-Davis et al., 2009; Ruhayel et al., 2010). Oedema: Ankle swelling is associated with loss of protein in the urine, which indicates renal failure, which is again due to the diabetes, hypertension and obesity. Due to the loss of protein in the urine, there is lower protein level in the blood of the patient, which leads to the ankle swelling. Due to hypoalbuminea there is the low capillary colloid oncotic pressure, which leads to the transfer of fluid from the vascular system to the interstitial fluid compartment and decreased circulatory volume. As a result, there is the compensatory renal sodium and water reabsorption, which leads to the development of oedema. Also kidney failure leads to the accumulation of fluid in the ankle region, which leads to the ankle swelling (Ellis, 2016). Metformin: Metformin is the first line treatment for the type 2 diabetes. Mentioned patient is consuming 500 mg BD metformin. Main action of metformin is through AMP-activated protein kinase (AMPK) activation, which prevents CREBCBPCRTC2 complex formation, resulting in the inhibition of gene transcription for gluconeogenesis. Along with hepatic glucose synthesis, metformin also enhances peripheral glucose uptake through the phosphorylation of Glucose transporter type 4 (GLUT4) (Pryor and Cabreiro, 2015). In addition to the type 2 diabetes, metformin is proved to be effective in the albuminuria in patients with diabetes mellitus which is one of the complications of the mentioned patient (Nasri and Rafieian-Kopaei, 2014). In previous studies, it has been shown that metformin is effective in weight reduction, however results from these studies were inconsistent (Park et al., 2009). Conclusion: This patient has type 2 diabetes since last 15 years, however it has not been taken care properly. Due to sustained high level of glucose this leads to the different conditions like hypertension, renal failure, blurred vision and oedema. Since, this patient worked as an accountant there is not much physical activity and moreover, there is less control over the diet and sedentary lifestyle, this patient became overweight over the time period. This overweight condition and along with the type 2 diabetes leads to different cardiovascular complications, nephropathy and retinopathy. Due to all these diseases, patient health condition becomes very complex and in this condition patient care should be done using an interdisciplinary team of respective departments. Along with medication, care should be provided to the patient in terms of diet, lifestyle changes and exercise. Because these conditions can be controlled by implementing all these strategies. References: Dharmashankar, K., Widlansky, M.E. (2010). Vascular Endothelial Function and Hypertension: Insights and Directions. Current Hypertension Reports, 12(6), 448455. Ellis, D. (2016). Pathophysiology, evaluation, and management of edema in childhood nephrotic syndrome. Frontiers in Pediatrics, 3, 111. Franchini, S., Savino, A., Marcovecchio, M.L., Tumini, S., Chiarelli, F., Mohn, A. (2015). The effect of obesity and type 1 diabetes on renal function in children and adolescents. Pediatric Diabetes, 16(6), 427-33. Gooch, J.L., Sharma, A.C. (2014). Targeting the immune system to treat hypertension: where are we? Current Opinion in Nephrology and Hypertension, 23(5), 473-9. Helal, I., Fick-Brosnahan, G.M., Reed-Gitomer, B., Schrier, R.W. (2012). 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Adipokine dysregulation, adipose tissue inflammation and metabolic syndrome. Molecular and Cellular Endocrinology , 314, 116. Mayer-Davis, E.J., Ma, B., Lawson, A, et al. (2009). Cardiovascular disease risk factors in youth with type 1 and type 2 diabetes: implications of a factor analysis of clustering. Metabolic syndrome and related disorders, 7(2), 8995. Mayer-Davis, E.J., Davis, C., Saadine, J., et al. (2012). Diabetic retinopathy in the SEARCH for Diabetes in Youth Cohort: a pilot study. Diabetic Medicine, 29(9), 114852. Mehri, S., Koubaa, N., Hammami, S., Mahjoub, S., Chaaba, R., Nakbi, A., et al. (2010). Genotypic interactions of renin-angiotensin system genes with diabetes type 2 in a Tunisian population. Life Sciences, 87, 4954. Muskiet, M.H.A. etal. (2014). The gutrenal axis: do incretin-based agents confer renoprotection in diabetes? Nature Reviews Nephrology, 10, 88103. Nasri, H., Rafieian-Kopaei, M. (2014). Metformin: Current knowledge. 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Pms (Pre-Menstrual Syndrome) Defense Essays - Menstrual Cycle

Pms (Pre-Menstrual Syndrome) Defense The question has been posed, ?What characteristics of employees, other than those explicitly covered by the Americans with Disabilities Act, can employers consider when hiring, firing, or promoting employees. This is a question that has become critical to answer, as ADA claims exceeded 91,000 in number between 1992 and 1997. Of these claims, the agency discovered reasonable cause to believe that discrimination occurred in only 3.1% of the cases. Many of these claims were built on seemingly weak foundations. Actual cases of discrimination have been brought (and denied) on claims of disability due to myopia, body odor, infertility, and ?anxiety brought on by admonishment from a supervisor.? Considering the costs of defending oneself against a claim, how likely are firms to capitulate to the specter of impropriety? Put another way, even if a firm believes that a candidate for hiring or promotion is not qualified for advancement, is the possibility of the candidate raising issue under the ADA enough to scare the company into selecting them? This question becomes even more convoluted when the malady in question is a legitimately recognized disability, but is itself an offshoot of some other syndrome. The PMS Defense Pre-menstrual syndrome (PMS) affects nearly all women at some point during their reproductive years. Fifty percent of women suffer from PMS regularly throughout their lives, and as many as 10% of women seek medical help to alleviate the symptoms of PMS. While the question of whether or not PMS is disabling is a contestable topic, the symptoms of PMS are widely accepted as having a debilitating effect on one's life functions. These symptoms range from headaches and insomnia to irritability and fatigue and their negative affect on one's ability to work at peak performance seems to be a reasonable inference. You will have to search under many rocks to find a company that will discriminate against a candidate on the basis of her suffering from PMS. But it seems reasonable for a company to consider factors such as ability to get along with other employees, attendance record, and consistency of performance when determining (as one example) which candidate to promote to a managerial position. The underlying biology of PMS gives credence to claims of it as a disability. While there are some ?corrective steps? women can take to mitigate the effects of PMS (such as a well balanced diet or vitamin supplements or other medical intervention), there is little to nothing that can be done to do away with PMS altogether. PMS is caused by a drop in progesterone levels or an increase in estrogen levels at a relatively predictable period during a woman's menstrual cycle. Implications for employers PMS has successfully been used as a defense in a criminal case in at least one incident. A Virginia state court accepted a woman's claim that PMS caused her to ?become intoxicated more easily? and justified her hostility towards a Virginia State Trooper who had pulled her over for erratic driving. Her lawyer successfully argued that her PMS had caused her to become ?more irritable and hostile than other people?. Lets assume for a moment that this is a reasonable ruling by the Virginia court, and PMS can be considered a disability protected by the ADA. What are the implications for employers? What are the ?reasonable accommodations? an employer might be expected to take to ensure a fair environment? To illustrate the difficulty of this situation, let's consider an industry where human interaction is the predominant responsibility, such as a retail establishment. The primary responsibility of a retail establishment, such as a restaurant or hotel, is customer service. The fundamental requirement of customer service is pleasant human interaction. In order for an individual to represent a company well, employees must maintain a professional demeanor throughout their dealings with the customer. If a woman suffering from PMS is more likely to be impatient or hostile with a customer, does an employer have the right to consider that? In this environment where the most basic duty of the job requires interaction, moving the employee to a ?back-office? job might be considered onerous and unreasonable. There may not be a back office job available that fits the particular skill set of the woman in question. In a service environment

The Young Holden essays

The Young Holden essays J.D. Salinger, an American novelist and a short story writer, introduces a peculiar and a very special strange young man in an outstanding novel labeled The Catcher in the Rye. A troubled teen named Holden Caulfield, at the age of 16, tries to maintain the purity and realness of life. He rejects the society around him and continuously describes people and their behavior as phonies. He constantly feels lonely, miserable, depressed and not to belong to the environment he lives in. Although he is very immature, he feels he has grown up and hates people when they expect him to be more mature. He is a troubled young boy who is having difficulties trying to survive in the world around him. He cares for weakness and pure innocence. This is shown in his affection towards little children and the ducks in Central Park. He is a very affectionate sensitive guy, however, he tries not to show this part of his character to the reader. Throughout the novel, Holden does not completely become mature. He keeps on remembering the death of his younger brother, Allie. Just because somebodys dead, you dont just stop liking them, for Gods sake-especially if they were about a thousand times nicer than the people you know thatre alive and all(J.D. Salinger, 171). He keeps on repeating how smart and nice he is. Although he thinks high of his parents, he avoids them. He is socially hopeless. He does know many people and have friends, but is unable to form real friendships that last long. He feels like the only person he can talk to his little sister, Phoebe You should see her. You never saw a little kid so pretty and smart in your whole life. Shes really smart. I mean shes had all(J.D. Salinger, 67). Holden likes when everything he leaves behind stays the same way. He loves going to the Museum of Natural History. He used to go there since he was a little kid. The museum is one of the plac...

Learn How to Conjugate Reposer (to Rest) in French

Learn How to Conjugate Reposer (to Rest) in French Meaning to rest, the French  reposer  will be a useful addition to your vocabulary. The verb will need to be conjugated, however, if you want to say things such as rested or resting. This lesson will introduce you to the essential conjugations youll need for  reposer. The Basic Conjugations of  Reposer Reposer is a regular -er verb, which means it follows the conjugation pattern of the majority of French verbs. If you have studied words like tomber (to fall), poser  (to put), or any other regular verb that ends in -er, this lesson should be relatively easy. The indicative mood is the best place to begin. This includes the basic present, future, and imperfect past tenses which are used most often in French. The catch is that you need to memorize a new word for every subject pronoun within each tense.   Step one in any conjugation is identifying the verb stem (or radical). For  reposer, that is  repos-. To this, a variety of endings are added that correspond to the subject and the tense. Using the chart, you can find which endings are required. For example,  I am resting is  je repose  while we will rest is  nous reposerons. Present Future Imperfect je repose reposerai reposais tu reposes reposeras reposais il repose reposera reposait nous reposons reposerons reposions vous reposez reposerez reposiez ils reposent reposeront reposaient The Present Participle of  Reposer The  present participle  of regular -er  verbs is very easy to form. All you have to do is add -ant  to the radical. For  reposer,  that produces the word  reposant. Reposer  in the Compound Past Tense Passà © composà © is the French compound past tense and its used frequently, so its very good to know. Forming it is rather easy as well. Begin by conjugating the auxiliary verb  avoir  into the present tense to match the subject. Youll then follow that with the  past participle  reposà ©, which does not change with the subject but does indicate that someone has already rested. For example, I rested is  jai reposà ©Ã‚  and we rested is  nous avons reposà ©. More Simple Conjugations of  Reposer When youre uncertain if the act of resting will take place, you can turn to either  the subjunctive  or  the conditional. The main difference here is that the conditional says the resting will only happen if something else occurs as well. The passà © simple  and  the imperfect subjunctive  are literary tenses. Youll find these almost exclusively in formal writing. Subjunctive Conditional Pass Simple Imperfect Subjunctive je repose reposerais reposai reposasse tu reposes reposerais reposas reposasses il repose reposerait reposa repost nous reposions reposerions reposmes reposassions vous reposiez reposeriez repostes reposassiez ils reposent reposeraient reposrent reposassent If you want to tell someone to Rest! or use  reposer  in a similarly assertive statement,  the French imperative  can be used. This is one of those rare times when you dont need the subject pronoun, so simplify it from  tu repose  to  repose. Imperative (tu) repose (nous) reposons (vous) reposez

Corrections and community justice Essay Example | Topics and Well Written Essays - 250 words

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